Description

Analgin Generic 500mg

Analgin 500 mg (Generic name: Metamizole or Dipyrone) is a non-opioid painkiller and fever reducer used in some countries for moderate to severe pain and high fever that doesn’t respond to other medications. While widely used in parts of Europe, Latin America, Asia, and Africa, it’s banned or restricted in several countries (like the U.S. and UK) due to concerns over serious blood-related side effects.

Quick Overview

• Generic name: Metamizole / Dipyrone

• Strength: 500 mg (tablet, injectable, or suppository)

• Drug class: Non-opioid analgesic and antipyretic

• Prescription status: Varies by country

• Brand names: Baralgin, Novalgin, Metamizol, others

Used For

• Moderate to severe pain (e.g., dental pain, injury, post-surgery)

• High fever (when not responsive to paracetamol or NSAIDs)

• Painful spasms (e.g., renal or biliary colic, often combined with antispasmodics)

How It Works

Analgin reduces pain and fever by inhibiting prostaglandin synthesis, similar to NSAIDs, but it also acts on the central nervous system, giving it both peripheral and central analgesic action.

How to Take It

• Typical adult dose: 500–1000 mg every 6–8 hours, as needed

• Max daily dose: ~4000 mg

• Available in oral, injectable, and suppository forms

• Should be taken with water, with or after meals

Common Side Effects

• Nausea or vomiting

• Dizziness

• Low blood pressure (especially with IV form)

• Skin rash or allergic reaction

Rare but Serious Risks

• Agranulocytosis: A rare but potentially fatal condition where white blood cells drop dangerously low, increasing infection risk

• Anaphylactic reactions (especially in people with asthma or NSAID allergy)

• Liver or kidney damage (rare, but possible with prolonged use)

Blood monitoring is sometimes recommended for long-term use to check for agranulocytosis.

Avoid If You Have:

• Known blood disorders

• History of NSAID or pyrazolone allergy

• Pregnancy (especially 3rd trimester)

• Liver or kidney dysfunction

• Risk factors for bone marrow suppression

 Availability Note

• Banned or restricted in: USA, UK, Canada, and others (due to agranulocytosis risk)

• Widely used in: Mexico, Brazil, Russia, India, Germany (with monitoring)

Summary

Analgin 500 mg is a powerful, fast-acting pain and fever reliever with fewer GI side effects than NSAIDs, but with rare, serious risks like agranulocytosis. It’s effective when other painkillers don’t work but should be used with caution—especially for long-term or unsupervised use.