Celebrex (Celecoxib) 200 mg is a prescription nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation, especially in arthritis and other musculoskeletal conditions. It’s unique among NSAIDs because it’s a COX-2 selective inhibitor, meaning it targets inflammation with less risk of stomach ulcers than traditional NSAIDs.

Quick Overview

• Generic name: Celecoxib

• Brand name: Celebrex

• Strength: 200 mg capsule (also comes in 100 mg)

• Class: NSAID – COX-2 selective

• Prescription only

Used For

• Osteoarthritis

• Rheumatoid arthritis

• Ankylosing spondylitis

• Menstrual cramps (primary dysmenorrhea)

• Acute pain (short-term injuries, dental pain, etc.)

• Juvenile arthritis (in specific age groups)

How It Works

Celecoxib blocks COX-2 enzymes, which are involved in pain and inflammation. Unlike older NSAIDs like ibuprofen and naproxen, Celebrex does not significantly inhibit COX-1, which helps protect the stomach lining. This makes it easier on the stomach for many patients.

How to Take It

• Typical adult dose:

  • 200 mg once daily, or

  • 100 mg twice daily, depending on condition and doctor’s advice

• Take with or without food

• For arthritis: may take several days to weeks to feel full benefits

• For pain: works within hours

Common Side Effects

• Upset stomach or diarrhea

• Headache

• High blood pressure (in some users)

• Dizziness or swelling in legs/feet

Serious Risks

• Increased risk of heart attack or stroke (especially at higher doses or with long-term use)

• Kidney problems, especially in older adults or dehydrated individuals

• Allergic reactions, particularly in those with sulfa allergies (Celebrex contains a sulfonamide group)

• GI bleeding, though risk is lower than traditional NSAIDs

Avoid If You Have:

• Known sulfa allergy

• History of heart disease, stroke, or GI bleeding

• Severe liver or kidney disease

Summary

Celebrex 200 mg is a powerful anti-inflammatory option for people who need long-term relief from arthritis or pain but are at risk of GI side effects from traditional NSAIDs. It’s not risk-free, especially for the heart, but can be a great choice when used responsibly.

Want help comparing Celebrex to ibuprofen, meloxicam, or naproxen? Or tips on managing inflammation without med