Description

Hydrocodone 10/325mg

Hydrocodone 10/325mg is a prescription opioid pain medication that combines:

• Hydrocodone 10 mg – a semi-synthetic opioid for moderate to severe pain

• Acetaminophen 325 mg – a non-opioid pain reliever and fever reducer (same active ingredient as Tylenol)

Together, they provide stronger and longer-lasting pain relief than either would alone.

Quick Facts

• Brand names: Norco, Lortab, Vicodin (depending on formulation)

• Class: Opioid analgesic + non-opioid analgesic

• Form: Oral tablets

• Controlled substance: Schedule II in the U.S. due to abuse potential

Used For

• Moderate to severe acute pain (e.g., surgery, injury, dental pain)

• Sometimes used for chronic pain, but with caution

• Not used for minor pain or long-term use unless no alternatives work

Typical Dosage

• Standard adult dose: 1 tablet every 4 to 6 hours as needed for pain

• Maximum acetaminophen limit: 4000 mg per day (to protect liver)
  → So max 12 tablets/day of 10/325 mg is a hard upper limit—often less is recommended

Common Side Effects

• Drowsiness or sedation

• Nausea, vomiting

• Constipation

• Lightheadedness or dizziness

• Itching

Serious Risks

• Respiratory depression (especially when mixed with alcohol or other sedatives)

• Addiction, abuse, or dependence

• Liver damage (from acetaminophen, especially in high doses or with alcohol)

• Withdrawal symptoms if stopped suddenly after regular use

Avoid If You Have:

• Severe asthma or breathing disorders

• Liver disease (especially if related to alcohol use)

• History of substance use disorder

• Current use of benzodiazepines, alcohol, or other CNS depressants Black Box Warnings

• Addiction and abuse risk (Schedule II controlled substance)

• Life-threatening respiratory depression

• Liver toxicity from acetaminophen

• Neonatal withdrawal syndrome if used during pregnancy

Summary

Hydrocodone 10/325 mg is a strong and effective opioid painkiller, commonly used after surgery or for serious injury. It must be taken exactly as prescribed, with full awareness of its risks for dependence and overdose, especially due to its acetaminophen component.

Would you like help comparing this to Percocet (Oxycodone/Acetaminophen) or info on non-opioid alternatives?