Description

Lexapro (Escitalopram) 20mg

Lexapro 20 mg is a higher-dose tablet of Escitalopram, a commonly prescribed SSRI (Selective Serotonin Reuptake Inhibitor) used to treat depression and anxiety disorders. It’s known for being well-tolerated, with relatively fewer side effects compared to older antidepressants.

Quick Overview

• Brand name: Lexapro

• Generic name: Escitalopram

• Strength: 20 mg

• Drug class: SSRI (Selective Serotonin Reuptake Inhibitor)

• Prescription required

Used For

• Major Depressive Disorder (MDD)

• Generalized Anxiety Disorder (GAD)

• Sometimes prescribed off-label for:

  • Panic disorder

  • OCD

  • Social anxiety disorder

  • PTSD

How It Works

Escitalopram increases serotonin levels in the brain by blocking its reuptake. Serotonin is a neurotransmitter that helps regulate mood, sleep, and emotional balance.

It is the S-enantiomer of citalopram, which makes it more potent and targeted, contributing to its effectiveness at relatively lower doses.

How to Take It

• Typical starting dose: 10 mg/day

• 20 mg/day is often the maximum dose, used when needed for stronger symptom control

• Taken once daily, with or without food

• Often taken in the morning to avoid insomnia, though some take it at night

• Takes 1–4 weeks to notice effects; up to 6–8 weeks for full benefit

• Do not stop suddenly—taper slowly to avoid withdrawal symptoms

Common Side Effects

• Nausea

• Headache

• Sleep issues (insomnia or drowsiness)

• Fatigue

• Dry mouth

• Increased sweating

• Decreased libido or sexual dysfunction

Serious Side Effects / Risks

• Suicidal thoughts, especially in young adults

• Serotonin syndrome (especially when combined with other serotonergic drugs)

• QT interval prolongation (affecting heart rhythm; rare)

• Withdrawal symptoms if stopped suddenly: dizziness, irritability, flu-like symptoms

• Mania or hypomania in people with bipolar disorder

 Drug Interactions

Avoid combining with:

• MAOIs (requires 14-day washout)

• Other SSRIs/SNRIs or serotonergic agents

• NSAIDs, aspirin, or blood thinners (may increase bleeding risk)

• Alcohol (can worsen drowsiness or mood instability)

 Summary

Lexapro 20 mg (Escitalopram) is a high-dose SSRI that’s often very effective for moderate to severe depression and anxiety. It has a reputation for being cleaner and more tolerable than many older antidepressants, but still requires monitoring for mood changes, especially when starting or adjusting the dose.